منابع مشابه
The Tau Code
In this short review, I will focus on how a unique tau gene may produce many tau isoforms through alternative splicing and how the phosphorylation of these isoforms by different kinases may affect their activity and behaviour. Indeed, each of the different tau isoforms may play a distinct role under both physiological and pathological conditions. Thus, I will discuss whether a tau code exists t...
متن کاملThe Dlr Tau-code: Recent Applications in Research and Industry
This paper gives an overview of the TAU-Code, DLR’s system for complex flow simulations on unstructured hybrid grids. Starting from a short description of the system and its components, e.g. mesh adaptation or grid deformation, its basic capabilities are discussed. Thereafter recent and on-going developments are presented, such as the adjoint approach or a pilot installation exploiting structur...
متن کاملPhospho-Tau Bar Code: Analysis of Phosphoisotypes of Tau and Its Application to Tauopathy
Tau is a microtubule-associated protein which regulates the assembly and stability of microtubules in the axons of neurons. Tau is also a major component of neurofibrillary tangles (NFTs), a pathological hallmark in Alzheimer's disease (AD). A characteristic of AD tau is hyperphosphorylation with more than 40 phosphorylation sites. Aggregates of hyperphosphorylated tau are also found in other n...
متن کاملCad-based Aerodynamic Shape Design Optimization with the Dlr Tau Code
With the improving capabilities of Computational Fluids Dynamics (CFD) on predicting aerodynamic performance, these tools are now being increasingly used for aerodynamic design optimization in the aerospace industry. In this paper, an automated optimization framework is presented to address inviscid aerodynamic design problems. Key aspects of this framework include the use of the continuous adj...
متن کاملMeasurements of the tau mass and the mass difference of the tau+ and tau- at BABAR
Citation Aubert, B. et al. " Measurements of the tau mass and the mass difference of the tau^{+} and tau^{-} at BABAR. Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matte...
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ژورنال
عنوان ژورنال: Frontiers in Aging Neuroscience
سال: 2009
ISSN: 1663-4365
DOI: 10.3389/neuro.24.001.2009